Tri-Adrenopan® - How it Works

Background

When the body is under stress for a prolonged period of time, it enters a stage of resistance which results in the continued stimulation of the adrenal glands by ACTH (adrenocorticotropic hormone, from the pituitary), causing accelerated release and synthesis of adrenal cortex hormones¹. This resistance stage allows the body to continue fighting stress long after the initial alarm reaction has occurred². The adrenal gland, when stimulated, also produces cortisol, a steroid hormone which is involved with the relief of pain and other symptoms in a variety of joint problems³.

It appears that pantothenic acid and vitamin C play a role in proper adrenal function and may assist in maintaining this function during extended periods of stress⁴. In addition, increased amounts of these vitamins as well as liver concentrates suggest an improvement in the capacity of animals to withstand stress^4,5,6,7. Vitamin B6 plays a role in the proper production and / or secretion of ACTH from the pituitary gland⁸. Because pantothenic acid and vitamin C are water soluble and present in large amounts, these ingredients have been designed to release slowly for prolonged effect

References

1. H. Selye, The Stress of Life, McGraw Hill, New York, (1976).
2. G.J. Tortora an N.P. Anignostakos, Principles of Anatomy and Physiology, Canfield Press, Sand Francisco (Dept. of Harper & Row, Publishers, Inc., New York), 1975., p. 331.
3. G.M. Grodsky, “Chemistry and Function of the Hormones: !. Thyroid, Pancreas, Adrenal and Gastrointestinal Tract”, in Review of Physiological Chemistry, by H.A. Harper, V.W. Rodwell and P.A. Mayes, Lange Medical Publications, Los Altos, CA, 1979., p. 511.
4. E.P. Ralii and M.E. Dunn, Relation of Pantothenic Acid to Adrenal Cortical Function”, Vitamins and Hormones, 11:133 (1953)
5. M.E. Dunn and Ralii, E.P., Metabolism, 2:153 (1953).
6. L.P. Dugal and M. Therian, Federation Proc., 11:38 (1953).
7. B. Ershoff, Proc. Soc. Exptl. Biol. Med. 77:488 (1951).
8. K. Guggenheim, “Studies on Water Metabolism of Pyridoxine and Pantothenic Acid Deficient Rats”, Endocrinology, 55:156 (1954).

Supplement Facts - Tri-Adrenopan®

Quality Assurance Statement - Anabolic Laboratories

Founded in 1924, Anabolic Laboratories formulates and manufactures clinical nutrition products. Our expertise in pharmaceutical manufacturing, patient programs, and clinician training sets the standard for health care professionals.

At Biossential Nutrition, we pride ourselves in offering the best products available to our customers. Offering the highest quality products & individual ingredients, as well as ensuring our products are effective & work as advertised, are the mains goals we strive to achieve with our product offerings.

Why We Recommend Anabolic Laboratories Nutritional Supplements

History

Anabolic Laboratories was founded as a nutritional products company in 1924 and became a pharmaceutical manufacturer in 1940. Anabolic Laboratories is one of the oldest manufacturers of nutritional products in the world.

Standards

As a pharmaceutical manufacturing operation, the standards used for raw materials, production and finished product testing exceed the new requirements for nutritional product manufacturing.

Quality

Pharmaceutical standards of manufacturing provide nutritional products with label accuracy, potency and purity as dictated by the USFDA (United States Food & Drug Administration).

Formulas

A nutritional program and clinical formulas that are based on the specifications used in the scientific research.

The Need To Consider Quality:

Of the magnesium supplements tested by ConsumerLab.com, 25% failed to meet quality standards. One magnesium supplement contained only 45.4% of labeled amount, despite boasting a "GMP" (Good Manufacturing Practices) seal on its label, and another supplement provided only 28.8% of the labeled amount.
Reference: ConsumerLab.com, Magnesium Supplement Reviews and Quality Ratings, Posted 5/19/09

Tests by ConsumerLab.com have found multivitamins that were short on ingredients, failed to dissolve properly, or were contaminated with heavy metals.
ConsumerLab.com, New Product Review: Multivitamin and Multimineral Supplements, Posted 4/1/09

The Food and Drug Administration (FDA) has found that manufacturing problems have been associated with dietary supplements. Products been recalled because of microbiological, pesticide, and heavy metal contamination, and because they do not contain the dietary ingredients they are represented to contain, or they contain more or less than the amount of dietary ingredient claimed on the label.
Reference: June 22, 2007, FDA @ http://www.cfsan.fda.gov/~dms/dscgmps7.html